How it works
AOD-9604 is a synthetic analog of the C-terminal fragment (residues 177–191) of human growth hormone, with an added N-terminal tyrosine. Unlike full-length GH it does not engage the GH receptor and produces no IGF-1-mediated effects. In animal models it has been studied for effects on β3-adrenergic signaling and lipolysis in adipose tissue. Its small size and lack of GH-receptor activity make it useful for isolating GH's lipolytic effects from its mitogenic ones.
Learn more about the science →Certificate of Analysis+
LC-MS identity, HPLC purity, endotoxin by LAL, mass spec confirmation. Third-party verified.
View full certificate →Specifications+
Storage & handling+
Lyophilized: −20°C, 24 months. Reconstituted: 2–8°C, 30 days. Bacteriostatic water.
We ship in insulated parcels with phase-change cooling and a tamper-evident seal.
FAQs+
Does AOD-9604 act on the GH receptor?+
No. The fragment lacks the structural elements required for GH receptor binding. This is the central distinction from full-length GH.
Why is AOD-9604 priced lower than the larger metabolic peptides?+
Smaller molecule, simpler synthesis. The price reflects synthesis cost, not quality — purity standards are identical to every other Metabo SKU.
What's the typical reconstitution concentration?+
Common preparation: 2 mL bacteriostatic water per 10mg vial, yielding 5 mg/mL.
How does AOD-9604 differ from CJC-1295 or sermorelin?+
Those act on the GHRH receptor to stimulate endogenous GH release. AOD-9604 mimics one specific lipolytic effect of GH directly, without engaging the GH axis.
What's the COA mass spec confirmation?+
Single peak at 1,815.1 g/mol, matching theoretical MW within assay tolerance.
Is AOD-9604 stable at room temperature briefly?+
Yes, briefly. Standard practice: 2–8°C storage, minimize ambient exposure during handling.
The research behind this compound, cited in full.
Provided for context only. None of the studies cited below evaluate hábit material specifically; they document the published literature on the compound and its mechanism. Research-use claims are not therapeutic claims.
- [01] Heffernan M. et al. Endocrinology 142 (2001): 5182–5189.
- [02] Ng FM. et al. Horm Res 53 (2000): 274–278.
- [03] The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment
- [04] Effect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis
Verified buyer notes
Initials only — every quote is verified against an order record. We don’t ghost-write reviews.
“COA matched what we ran in-house. Powder reconstituted clean, no haze. Did exactly what we needed it to.”
“Switched after two bad lots from a previous source. Three orders in, zero issues.”
“Asked support a purity question and got the raw HPLC trace back within the hour. That transparency is why we reorder.”