How it works.

Ipamorelin is a synthetic pentapeptide that selectively agonizes the ghrelin/GHS receptor (GHS-R1a) on anterior-pituitary somatotrophs, stimulating growth-hormone release. Its defining property is selectivity: unlike earlier growth-hormone-releasing peptides, published research reports little to no elevation of ACTH, cortisol, or prolactin at GH-releasing doses, producing a cleaner stimulus for studies isolating the GH axis.

IpamorelinGHS-R1a (ghrelin R)
somatotrophsselective GH release
≠ ACTH / PRLminimal cortisol · prolactin
From researchers using Ipamorelin

Verified buyer notes.

Initials only — every quote is verified against an order record. We don’t ghost-write reviews.

COA matched what we ran in-house. Powder reconstituted clean, no haze. Did exactly what we needed it to.
M.O.Boston, MAApril 2026
Switched after two bad lots from a previous source. Three orders in, zero issues.
J.K.Austin, TXMarch 2026
Shipment got delayed two days by weather and still arrived at 4°C. Packaging is no joke.
R.A.Seattle, WAFebruary 2026