For laboratory and research use only. Not for human or animal consumption.

How it works

Kisspeptin-10 is the biologically active C-terminal decapeptide of kisspeptin, the product of the KISS1 gene. It is a high-affinity agonist of KISS1R (formerly GPR54) on hypothalamic GnRH neurons. Activation stimulates pulsatile GnRH release, positioning kisspeptin as a principal upstream regulator of the hypothalamic-pituitary-gonadal axis. In published research it is characterized for effects on downstream LH and FSH secretion and as a tool for probing HPG-axis signaling.

Learn more about the science →
KISS1 gene productactive C-terminal decapeptide
KISS1R (GnRH neurons)pulsatile GnRH release
↑ LH / FSHHPG-axis regulation
Certificate of Analysis+

LC-MS identity, HPLC purity (≥99%), mass spec confirmation, endotoxin by LAL, appearance. Third-party ISO-17025 verified.

View full certificate →Lot KIS-2607-P · Jul 2026 · printable
Purity (HPLC)99.1%✓ Pass
Mass spec (MW)1,302.45✓ Pass
Endotoxin (LAL)<0.5 EU/mg✓ Pass
Certificate metadata
Lot
KIS-2607-P
Released
Jul 2026
Tested by
Janus Analytical (ISO-17025)
Method
RP-HPLC · LC-MS · LAL · KF
Specifications+
CompoundKisspeptin-10 (metastin 45-54)
CAS374675-21-5
FormLyophilized
Purity≥99% by HPLC
Endotoxin<0.5 EU/mg
Storage & handling+

Lyophilized: −20°C, 24 months. Reconstituted: 2–8°C, use within 30 days. Reconstitute with bacteriostatic water; swirl gently, protect from light.

We ship in insulated parcels with phase-change cooling and a tamper-evident seal.

FAQs+
Why is Kisspeptin in Longevity Research?+

Longevity Research collects compounds studied for systemic vitality and central regulatory pathways. Kisspeptin is a master upstream regulator of the HPG (hypothalamic-pituitary-gonadal) neuroendocrine axis, which places it in that scope.

What is KISS1R?+

KISS1R (formerly GPR54) is the G-protein-coupled receptor for kisspeptin on hypothalamic GnRH neurons. Its activation is the trigger for pulsatile GnRH release.

What's a typical reconstitution concentration?+

Investigator-dependent. A common preparation is 1 mL bacteriostatic water per 10mg vial, yielding 10 mg/mL.

How is identity confirmed on the COA?+

Mass spec against the theoretical mass of 1,302.45 g/mol, HPLC purity, and a third-party ISO-17025 repeat assay.

Is Kisspeptin-10 stable in solution?+

Yes, with standard cold storage. 30 days at 2–8°C is the operating spec.

Is Kisspeptin-10 subscription-eligible?+

Yes. 15% off on a 60-day cycle once it returns to stock.

The research behind this compound, cited in full.

Provided for context only. None of the studies cited below evaluate hábit material specifically; they document the published literature on the compound and its mechanism. Research-use claims are not therapeutic claims.

  1. [01] de Roux N. et al. Proc Natl Acad Sci USA 100 (2003): 10972–10976.
  2. [02] Dhillo WS. et al. J Clin Endocrinol Metab 90 (2005): 6609–6615.
  3. [03] Skorupskaite K. et al. Hum Reprod Update 20 (2014): 485–500.

Verified buyer notes

Initials only — every quote is verified against an order record. We don’t ghost-write reviews.

COA matched what we ran in-house. Powder reconstituted clean, no haze. Did exactly what we needed it to.
M.O.Boston, MAApril 2026
Switched after two bad lots from a previous source. Three orders in, zero issues.
J.K.Austin, TXMarch 2026
Asked support a purity question and got the raw HPLC trace back within the hour. That transparency is why we reorder.
S.L.Chicago, ILFebruary 2026