How it works
NAD+ is a coenzyme present in every living cell, central to redox reactions in glycolysis, the TCA cycle, and oxidative phosphorylation. It is also a substrate for sirtuins, PARPs, and CD38 — enzymes implicated in DNA repair, gene expression regulation, and aging biology. Cellular NAD+ levels decline with age in mammalian tissue; restoring or supplementing NAD+ in research models has produced measurable effects on mitochondrial respiration and sirtuin-dependent transcription.
Learn more about the science →Certificate of Analysis+
Identity by HPLC retention time and UV absorbance (340 nm peak post-reduction), purity by HPLC (≥99%), endotoxin by LAL, residual solvent screening, appearance. Third-party ISO-17025 verified.
View full certificate →Specifications+
Storage & handling+
Lyophilized: −20°C, 24 months. Reconstituted: 2–8°C, use within 14 days — NAD+ degrades faster in solution than most peptides. Reconstitute with sterile water or saline. Avoid bacteriostatic water for IV-route research. Solutions are pH-sensitive; do not adjust below pH 7.
We ship in insulated parcels with phase-change cooling and a tamper-evident seal.
FAQs+
Why is NAD+ less stable in solution than peptides?+
The pyridine ring is susceptible to hydrolysis at physiological pH. Cold storage and short post-reconstitution windows are standard.
What's the difference between NAD+ and NMN or NR?+
NMN and NR are precursors that cells convert to NAD+ via the salvage pathway. NAD+ itself is the active cofactor. Each has different bioavailability profiles.
Why a 1000mg vial?+
NAD+ research protocols typically use higher mass than peptide studies. The 1000mg vial reflects the working dose range in published in-vivo work.
Is the third-party verification standard for NAD+?+
Yes. Every Neuro SKU goes through the same ISO-17025 cycle as the peptide line.
Can NAD+ be co-administered with other Neuro compounds in research?+
Investigator-dependent. The COA documents identity and purity; combining is a research-design decision.
What's the appearance of properly reconstituted NAD+?+
Clear, colorless to faintly yellow. Cloudiness, particulates, or strong color indicate degradation — discard.
The research behind this compound, cited in full.
Provided for context only. None of the studies cited below evaluate hábit material specifically; they document the published literature on the compound and its mechanism. Research-use claims are not therapeutic claims.
- [01] Verdin E. Science 350 (2015): 1208–1213.
- [02] Rajman L. et al. Cell Metab 27 (2018): 529–547.
- [03] Yoshino J. et al. Cell Metab 27 (2018): 513–528.
- [04] Association of Human Whole Blood NAD+ Contents With Aging
Verified buyer notes
Initials only — every quote is verified against an order record. We don’t ghost-write reviews.
“COA matched what we ran in-house. Powder reconstituted clean, no haze. Did exactly what we needed it to.”
“Switched after two bad lots from a previous source. Three orders in, zero issues.”
“Asked support a purity question and got the raw HPLC trace back within the hour. That transparency is why we reorder.”