How it works
SS-31 (elamipretide) is a synthetic tetrapeptide with an alternating aromatic-cationic motif that lets it cross cell membranes and concentrate several-thousand-fold in the inner mitochondrial membrane. There it associates selectively with cardiolipin, the signature phospholipid of the inner membrane. In published research this interaction is linked to stabilization of cristae architecture, improved electron-transport-chain coupling, and reduced mitochondrial reactive-oxygen-species output in models of age- and stress-related mitochondrial dysfunction.
Learn more about the science →Certificate of Analysis+
LC-MS identity, HPLC purity (≥99%), mass spec confirmation, endotoxin by LAL, appearance. Third-party ISO-17025 verified.
View full certificate →Specifications+
Storage & handling+
Lyophilized: −20°C, 24 months. Reconstituted: 2–8°C, use within 30 days. Reconstitute with bacteriostatic water; swirl gently, protect from light.
We ship in insulated parcels with phase-change cooling and a tamper-evident seal.
FAQs+
Why is SS-31 categorized under Longevity Research?+
Longevity Research collects compounds studied for systemic vitality and cellular function. SS-31 binds cardiolipin on the inner mitochondrial membrane, and its research context is cellular bioenergetics broadly rather than any one tissue.
What makes SS-31 mitochondria-targeting?+
Its alternating aromatic-cationic residues drive membrane permeability and accumulation in the inner mitochondrial membrane, where it associates with cardiolipin — no carrier or transporter required.
What is cardiolipin's role?+
Cardiolipin is the inner-membrane phospholipid that scaffolds the electron-transport chain. SS-31's association with it is the proposed basis for its effects on cristae structure and coupling.
What's a typical reconstitution concentration?+
Investigator-dependent. A common preparation is 2 mL bacteriostatic water per 50mg vial, yielding 25 mg/mL.
How is SS-31 quality verified?+
LC-MS identity and HPLC purity on every lot, mass spec against the theoretical mass, and a third-party ISO-17025 repeat assay.
Is SS-31 subscription-eligible?+
Yes. 15% off on a 60-day cycle once it returns to stock.
The research behind this compound, cited in full.
Provided for context only. None of the studies cited below evaluate hábit material specifically; they document the published literature on the compound and its mechanism. Research-use claims are not therapeutic claims.
- [01] Szeto HH. Br J Pharmacol 171 (2014): 2029–2050.
- [02] Birk AV. et al. J Am Soc Nephrol 24 (2013): 1250–1261.
- [03] Chatfield KC. et al. Mitochondrion 49 (2019): 102–112.
Verified buyer notes
Initials only — every quote is verified against an order record. We don’t ghost-write reviews.
“COA matched what we ran in-house. Powder reconstituted clean, no haze. Did exactly what we needed it to.”
“Switched after two bad lots from a previous source. Three orders in, zero issues.”
“Asked support a purity question and got the raw HPLC trace back within the hour. That transparency is why we reorder.”