How it works
Bremelanotide is a synthetic analog of α-MSH, engineered as a cyclic heptapeptide with selective agonist activity at MC3R and MC4R melanocortin receptors. Unlike PDE5 inhibitors, which act on vascular smooth muscle, its mechanism is centrally mediated — its receptor activity is in the hypothalamus, not the periphery. Research has documented central melanocortin-pathway activity in animal and clinical models, with a pharmacokinetic profile suited to subcutaneous administration in research protocols.
Learn more about the science →Certificate of Analysis+
LC-MS identity, HPLC purity, mass spec confirmation, endotoxin, appearance. Third-party ISO-17025 verified.
View full certificate →Specifications+
Storage & handling+
Lyophilized: −20°C, 24 months. Reconstituted: 2–8°C, 30 days. Bacteriostatic water.
We ship in insulated parcels with phase-change cooling and a tamper-evident seal.
FAQs+
Why is Bremelanotide in Vita rather than Neuro?+
Vita covers broad-spectrum compounds studied for systemic effects on vitality and central regulatory pathways. Bremelanotide acts centrally on melanocortin receptors with effects on neuroendocrine output — that scope sits more cleanly in Vita than in Neuro, which we've kept narrower for cofactor and mitochondrial work.
How does Bremelanotide differ from PDE5 inhibitors?+
Different mechanism entirely. Bremelanotide acts on MC3R/MC4R in the central nervous system. PDE5 inhibitors act on vascular smooth muscle.
Is Bremelanotide subscription-eligible?+
Not at launch. Most research protocols using it are intermittent rather than continuous.
What's the typical reconstitution volume?+
Common preparation: 1 mL bacteriostatic water per 10mg vial, yielding 10 mg/mL.
How is Bremelanotide different from Melanotan-II?+
Melanotan-II has broader receptor activity (MC1R included), producing pigmentation effects Bremelanotide largely avoids. Bremelanotide is more selective for MC3R/MC4R.
What COA data is most relevant for Bremelanotide?+
Mass spec confirmation against 1,025.18 g/mol is the key identity check, since the compound has known impurity profiles that mass spec resolves cleanly.
The research behind this compound, cited in full.
Provided for context only. None of the studies cited below evaluate hábit material specifically; they document the published literature on the compound and its mechanism. Research-use claims are not therapeutic claims.
- [01] Diamond LE. et al. Int J Impot Res 16 (2004): 51–59.
- [02] King SH. et al. Pharmacol Biochem Behav 87 (2007): 425–430.
- [03] Molinoff PB. et al. Ann N Y Acad Sci 994 (2003): 96–102.
- [04] Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials
Verified buyer notes
Initials only — every quote is verified against an order record. We don’t ghost-write reviews.
“COA matched what we ran in-house. Powder reconstituted clean, no haze. Did exactly what we needed it to.”
“Switched after two bad lots from a previous source. Three orders in, zero issues.”
“Asked support a purity question and got the raw HPLC trace back within the hour. That transparency is why we reorder.”